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Microvillis and zonulaoccludens were observed on the surface of the differentiated cells under an electron microscope.
2
Most gap junctions between neurons in mammalian retina contain abundant connexin36, often in association with the scaffolding protein zonulaoccludens-1.
3
The expression and membrane localization of the tight junction proteins zonulaoccludens-1 and occludin were decreased in alveolar epithelial cells from HIV-1 transgenic rats.
1
Sequestration of CAR in tightjunctions may limit virus infection across epithelial surfaces.
2
They create tightjunctions with mouse hepatocytes, with no evidence of cell fusion.
3
This isoform of TOCA-1 recruits the actin nucleation-promoting factor N-WASP to tightjunctions.
4
JAM-A localizes to tightjunctions and contributes to paracellular permeability in polarized epithelia.
5
Adherens junctions are calcium dependent; recent evidence suggests that calcium also affects tightjunctions.
Usage of tight junction in English
1
Proposed roles include maintenance of tightjunction barriers, signaling and junction remodeling.
2
PKC-ζ inhibition also attenuated AGE-induced decrease of tightjunction proteins in HRMECs.
3
Results showed reversible recovery on the expression of tightjunction markers.
4
Proteins responsible for tightjunction integrity are upregulated in hypertonic states.
5
The tightjunction of epithelial cells excludes macromolecules but allows permeation of ions.
6
Occludin is a transmembrane protein of the tightjunction with two extracellular loops.
7
Claudin-1 is a tightjunction-associated protein recently shown to be expressed in anaplastic meningiomas.
8
Tissue barrier function is directly mediated by tightjunction transmembrane proteins known as claudins.
9
Epithelial barrier function is maintained by tightjunction proteins that control paracellular fluid flux.
10
A different mechanism of tightjunction disruption in CF versus non-CF epithelia was found.
11
This therapy recovered the tightjunction protein and mitigated bacterial translocation and lipopolysaccharides levels.
12
Claudins are cell adhesion proteins thought to mediate cell-cell contacts at the tightjunction.
13
Our results support the hypothesis that discrete ion channels are present at the tightjunction.
14
Our results suggest that BN-PAGE may be a useful tool in understanding tightjunction structure.
15
Results: Mino treatment significantly inhibited IR-induced retinal vascular permeability and disruption of tightjunction organization.
16
Moreover, apical MMP9 treatment decreased immunostaining of tightjunction proteins suggesting disruption of barrier function.